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The complex 7 exhibits an intense 1 MLCT absorption band at nm and luminesces at nm with a luminescence quantum yield of 3. The fluorescence microscopy imaging study of HeLa cells incubated with 7 and stained with ethidium bromide and acridine orange confirms that the cells are viable throughout the imaging experiments and its cytotoxicity against HeLa cells, studied by the MTT assay, demonstrates its use for bioimaging studies. Furthermore, apoptosis of HeLa cells, studied by the DNA ladder assay, indicates apoptotic cell death lending support for the antitumor activity of 7. A molecular docking study reveals that the complex 7 intercalates into the major groove of the DNA stabilized by hydrogen bonding and it binds with HSA by electrostatic- and hydrogen bonding interactions. The relaxometry, luminescence and fluorescence imaging studies indicate that the Ru II —Gd III 2 complex 7 has a good cell membrane permeability and could be considered as a potential bimodal imaging probe. The article was received on 04 Jun , accepted on 03 Sep and first published on 07 Sep
Unnikrishnan , Revathy , Anjali Menon , M. Padmakumar , Shankar Ramakrishnan, and Uday Ananthan. For the first time in Malayalam cinema, one film was conceived by a team of ten directors. Ten cinematographers, musicians, editors, art directors and almost all the top Malayalam film actors joined this unique venture. The film released in Kerala on 29 October On a common theme of journeys, each filmmaker presents their cinematic impression of contemporary times in Kerala. The independent narratives integrate when, during these journeys, their characters pass through Kerala Cafe—a quaint railway cafeteria—thereby creating a joint mosaic of issues and impressions.
The List of Sandilyan Novels Free Download PDF is Below. Novel Name View Download Link Aalai Aarasi Avani Sundari Chandramathi Cheran. Read More» .
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August 9, 2018
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We got a furry little baby in June last year. We named him Bruno. He is a cuddly little golden retriever. He was my joy. He was my lucky charm. August got me realizing that I was pregnant.
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